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The therapeutic effects of DermaSilk have been extensively studied by clinicians throughout Europe and their findings published in "peer reviewed" academic medical journals. This means that the results demonstrated in the trials have been independently assessed as accurate by other doctors. The sections below give a brief description of the studies undertaken and the results obtained. No other product of this type has gone through such exhaustive tests to validate its effectiveness. DermaSilk continues to be researched in a wide range of medical conditions and future publications will be added when appropriate.



Clinical effectiveness of a silk fabric in the treatment of atopic dermatitis.
Ricci, G and colleagues from Bologna University Hospital, Italy.
Published in British Journal of Dermatology. 2004. Issue 150. Pages 127 - 131

The purpose of this study was to evaluate the effectiveness of DermaSilk in the treatment of young children affected by atopic dermatitis at the time of examination.

Forty six children, aged between 4 months and 10 years old with atopic dermatitis were recruited and randomised to DermaSilk (31 patients) or cotton clothing (15 patients) to be worn continuously for a week. The only other medicines prescribed were topical moisturisers. No steroid creams or topical antibiotics were prescribed.

The severity of the eczema was measured by the SCORAD index, a scientific way of measuring a mixture of physical and social effects that atopic dermatitis has on patients. The doctors measuring these scores were not aware which garments the patients were using.

At the end of the study the SCORAD index of the DermaSilk group had significantly decreased from 47 to 30 whilst the cotton wearing group had moved from 47 to 46.

83% of children using the DermaSilk had shown an improvement in their overall condition, whereas none of the cotton wearing children had shown any improvement.

Areas of eczema which were present on the DermaSilk clothed children but which had not been covered by DermaSilk were also examined as a control. They did not show any significant improvement over the week suggesting that it was, indeed the covering of the eczema with DermaSilk that was having the beneficial effect.

The authors concluded that DermaSilk appeared to significantly improve the condition of eczema lesions and that the parents of these children also reported a reduction in itching and scratching.

DermaSilk appears to have a rapid effect on the symptoms of atopic dermatitis in children, showing a positive effect in only 7 days in over 80% of children and may represent a useful tool in the management of the disease.                                                                                                <<return to top

DermaSilk Clinical effectiveness of a silk fabri c in the treatment of atopic dermatitis


 

Action of a silk fabric treated with AEGIS in children with atopic dermatitis: A 3-month trial

Koller DY, Halmerbauer G, Bock A, Engstler G.
Published in Pediatric Allergy & Immunology 2007.

Method  

The aim of the study was to evaluate the clinical effect of
Dermasilk in children with atopic dermatitis.

A total of 22 children with mild-to-moderate atopic dermatitis were recruited for a study period of 3 months. All of them received three different tube-fabrics

  • Dermasilk,
  • A sericin-free silk fabric without AEGIS AEM 5772/5
  • and cotton.

These tubes were placed on the bend of each arm over the elbow. Patients were advised to wear the Dermasilk fabric all day long during the whole study period on one arm. On the other arm the sericin-free AEGIS-free silk tube had to be used during the first 2 weeks of the study and replaced with the cotton tube for the rest of the study period.

Evaluation of the local SCORAD score was carried out at the beginning of the study, after 2, 4, 8 and 12 weeks.

Results. Conclusions.

A significant reduction of the local SCORAD index of the Dermasilk covered arm was observed after 4, 8 and 12 weeks in comparison with the cotton-covered arm score.

No adverse effects were observed by the doctors or reported by the parents. It was also demonstrated that the effectiveness of Dermasilk was not reduced by laundering, although the tubes were washed daily.

 

Dermasilk is useful in the treatment of mild-to-moderate atopic dermatitis in children This effectiveness continued over the whole 12 week trial indicating that usage over a long period will continue to help. The effectiveness is because of the characteristics of the fabric.

Silk enhances collagen synthesis and reduces inflammatory processes. The authors comment that "Normal" silk fabrics used for clothes are not recommended for dressing of subjects with atopic dermatitis, as these fabrics reduce transpiration and therefore may cause worsening of disease activity.

This statement highlights the need for knitted Sericin-free silk - DermaSilk.